Stanislav Smr?ek research activities on the field of biotransformations of organic xenobiotics in plant cultures, currently pharmaceuticals form the groups of non-steroidal inflammatory drugs and antidepressants. In vitro phytoremediation models concerning pharmaceuticals and engineered nanoparticles in wastewaters and environment including translocation studies. The synthesis and use of radioactive labelled compounds and their use in biochemistry. The evaluation of and environmental impact of radiopharmaceuticals.